|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Glucosidase, Alpha; Neutral AB (GANAB) (N-Term) antibody
|Synonyms||G2AN, GLUII, KIAA0088, G2an, GANAB, Hbg1, GB12607|
Alternatives Western Blotting (WB), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This GANAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-120 amino acids from the N-terminal region of human GANAB.|
|Description||Other names: Neutral alpha-glucosidase AB,GANAB,KIAA0088, G2AN|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This GANAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-120 amino acids from the N-terminal region of human GANAB.|
|Molecular Weight||106874 DA|
Background: Glucosidase II is an endoplasmic reticulum localized enzyme that has an important function in the folding and maturation of glycoproteins. Glucosidase II is composed of two soluble proteins: a catalytic alpha-subunit and a beta-subunit of unknown function, both of which are highly conserved in mammals.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Restrictions||For Research Use only|
Martiniuk, Ellenbogen, Hirschhorn: "Identity of neutral alpha-glucosidase AB and the glycoprotein processing enzyme glucosidase II. Biochemical and genetic studies." in: The Journal of biological chemistry, Vol. 260, Issue 2, pp. 1238-42, 1985 (PubMed).
Martiniuk, Smith, Ellenbogen et al.: "Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11." in: Cytogenetics and cell genetics, Vol. 35, Issue 2, pp. 110-6, 1983 (PubMed).
Trombetta, Simons, Helenius: "Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit." in: The Journal of biological chemistry, Vol. 271, Issue 44, pp. 27509-16, 1996 (PubMed).
|Reactivities||Human (10), Mouse (Murine) (2)|
|Applications||Western Blotting (WB) (10), Immunoprecipitation (IP) (3), ELISA (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2)|
|Epitopes||AA 916-930 (3), Internal Region (1), N-Term,AA 91-120 (1)|