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Class B Basic Helix-Loop-Helix Protein 3 (BHLH3) (AA 17-46), (N-Term) antibody

Details for Product No. ABIN651934, Supplier: Log in to see
Antigen
Epitope
AA 17-46, N-Term
9
7
1
Reactivity
Human
9
Host
Rabbit
9
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
8
7
7
1
Supplier
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Immunogen This BHLH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 AA from the N-terminal region of human BHLH3.
Clone RB19405
Isotype Ig
Specificity This BHLH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-54 amino acids from the N-terminal region of human BHLH3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BHLH3
Background BHLHE41 may be a transcriptional repressor that represses both basal and activated transcription.
Synonyms: Class E basic helix-loop-helix protein 41,BHLHE41,SHARP1, DEC2, BHLHB3
Molecular Weight 50498 DA
Gene ID 79365
NCBI Accession NP_110389
UniProt Q9C0J9
Research Area Translation Factors, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.3 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Class B Basic Helix-Loop-Helix Protein 3 (BHLH3) (AA 17-46), (N-Term) antibody (ABIN651934) BHLH3 Antibody (N-term) (ABIN651934) western blot analysis in NCI-H460 cell line lysa...
Western Blotting (WB) image for anti-Class B Basic Helix-Loop-Helix Protein 3 (BHLH3) (AA 17-46), (N-Term) antibody (ABIN651934) BHLH3 Antibody (N-term) (ABIN651934) western blot analysis in mouse cerebellum tissue...
Flow Cytometry (FACS) image for anti-Class B Basic Helix-Loop-Helix Protein 3 (BHLH3) (AA 17-46), (N-Term) antibody (ABIN651934) BHLH3 Antibody (N-term) (ABIN651934) flow cytometric analysis of NCI-H460 cells (righ...
Background publications Honma, Kawamoto, Takagi et al.: "Dec1 and Dec2 are regulators of the mammalian molecular clock." in: Nature, Vol. 419, Issue 6909, pp. 841-4, 2002 (PubMed).

Garriga-Canut, Roopra, Buckley: "The basic helix-loop-helix protein, sharp-1, represses transcription by a histone deacetylase-dependent and histone deacetylase-independent mechanism." in: The Journal of biological chemistry, Vol. 276, Issue 18, pp. 14821-8, 2001 (PubMed).

Fujimoto, Shen, Noshiro et al.: "Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins." in: Biochemical and biophysical research communications, Vol. 280, Issue 1, pp. 164-71, 2001 (PubMed).

Grottke, Mantwill, Dietel et al.: "Identification of differentially expressed genes in human melanoma cells with acquired resistance to various antineoplastic drugs." in: International journal of cancer. Journal international du cancer, Vol. 88, Issue 4, pp. 535-46, 2000 (PubMed).