Zinc Finger, FYVE Domain Containing 22 (ZFYVE22) (Center) antibody

Antigen: Zinc Finger, FYVE Domain Containing 22 (ZFYVE22)

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN651969

Additional Information

Alternative name: WDFY2

Gene ID: 115825

UniProt: NP_443182.1, Q96P53

Immunogen: This WDFY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human WDFY2.

Isotype: Ig

Description: Other names: WD repeat and FYVE domain-containing protein 2,WDFY2,ZFYVE22, WDF2

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This WDFY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human WDFY2.

Molecular Weight: 45154 DA

Comments:

Background: WDFY2 is a protein that contains two WD domains and an FYVE zinc finger region. The function of this gene is unknown. An alternatively spliced transcript variant of this gene may exist.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure

Restrictions: For Research Use only

Images

WDFY2 Antibody (Center) (ABIN651969) western blot analysis in mouse kidney tissue lysates (15ug/lane). This demonstrates the WDFY2 antibody detected WDFY2 protein (arrow).

WDFY2 Antibody (Center) (ABIN651969) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the WDFY2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Hayakawa, Leonard, Murphy et al.: "The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 32, pp. 11928-33, 2006 (PubMed).

Fritzius, Frey, Schweneker et al.: "WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta." in: The FEBS journal, Vol. 274, Issue 6, pp. 1552-66, 2007 (PubMed).