ST14 antibody (C-Term)

Catalog No. ABIN652185

Product Details anti-ST14 Antibody

Target: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Binding Specificity: AA 826-855, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ST14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-855 amino acids from the C-terminal region of human ST14.

Clone: RB2080

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ST14

Target: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Alternative Name: ST14 (ST14 Products)

Synonyms: HAI antibody, MT-SP1 antibody, MTSP1 antibody, PRSS14 antibody, SNC19 antibody, TADG15 antibody, TMPRSS14 antibody, XMT-SP1 antibody, hai antibody, mt-sp1 antibody, mtsp1 antibody, prss14 antibody, snc19 antibody, st14 antibody, st14a antibody, tadg15 antibody, tmprss1 antibody, Epithin antibody, Prss14 antibody, Tmprss14 antibody, mCAP3 antibody, matriptase antibody, suppression of tumorigenicity 14 antibody, suppression of tumorigenicity 14 L homeolog antibody, suppression of tumorigenicity 14 (colon carcinoma) antibody, ST14 antibody, st14.L antibody, St14 antibody

Background: ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Molecular Weight: 94770

Gene ID: 6768

NCBI Accession: NP_068813

UniProt: Q9Y5Y6