HOMER3 antibody (AA 281-308)

Catalog No. ABIN652274

Product Details anti-HOMER3 Antibody

Target: HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))

Binding Specificity: AA 281-308

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOMER3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HOMER3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human HOMER3.

Clone: RB21915

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-HOMER3 antibody (ABIN652274)

Shimobayashi, Wagner, Kapfhammer: "Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKC? Activity and Regulates Purkinje Cell Dendritic Growth." in: Molecular neurobiology, (2015) (PubMed).

Target Details for HOMER3

Target: HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))

Alternative Name: HOMER3 (HOMER3 Products)

Background: HOMER3 is a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. This protein binds numerous other proteins including group I metabotropic glutamate receptors,inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides.

Molecular Weight: 39836

Gene ID: 9454

NCBI Accession: NP_001139193, NP_001139194, NP_001139196, NP_004829

UniProt: Q9NSC5