PCSK9 antibody (N-Term)

Catalog No. ABIN652320

Product Details anti-PCSK9 Antibody

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Binding Specificity: AA 153-183, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK9 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCSK9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-183 amino acids from the N-terminal region of human PCSK9.

Clone: RB19130

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:500-1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PCSK9

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Alternative Name: PCSK9 (PCSK9 Products)

Synonyms: FH3 antibody, HCHOLA3 antibody, LDLCQ1 antibody, NARC-1 antibody, NARC1 antibody, PC9 antibody, AI415265 antibody, AI747682 antibody, Narc1 antibody, proprotein convertase subtilisin/kexin type 9 antibody, proprotein convertase subtilisin/kexin type 9 L homeolog antibody, PCSK9 antibody, pcsk9.L antibody, pcsk9 antibody, Pcsk9 antibody

Background: PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

Molecular Weight: 74286

Gene ID: 255738

NCBI Accession: NP_777596

UniProt: Q8NBP7