Vitronectin (VTN) (N-Term), (AA 65-93) antibody

Details for Product No. ABIN652347
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Antigen
Synonyms VN, V75, VNT, Vn, AI256434, Aa1018, VTN, DKFZp470F0511, LOC100228142, vtn, zgc:112277
Epitope
N-Term, AA 65-93
(5), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(142), (44), (23), (17), (13), (2), (1), (1), (1), (1)
Host
Rabbit
(93), (69), (11), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(137), (90), (25), (23), (17), (16), (12), (11), (11), (11), (10), (6), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN652347
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 AA from the N-terminal region of human VTN.
Clone RB17843
Isotype Ig
Specificity This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72~101 amino acids from the N-terminal region of human VTN.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VTN
Background VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Synonyms: Vitronectin, Serum-spreading factor, S-protein, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B , VTN
Pathways: Focal adhesion, ECM-receptor interaction
Molecular Weight 54,306 Da
Gene ID 7448
UniProt P04004
Research Area Signaling, Cancer
Application Notes WB = 1:1000, IHC = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.34 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Vitronectin (VTN) (N-Term), (AA 65-93) antibody Western blot analysis of VTN Antibody (N-term) (ABIN652347) in NCI-H460 cell line lysates (35 µg/lane). VTN (arrow) was detected using the purified polyclonal antibody.
anti-Vitronectin (VTN) (N-Term), (AA 65-93) antibody (2) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with VTN Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Vitronectin (VTN) (N-Term), (AA 65-93) antibody (3) VTN Antibody (N-term) (ABIN652347) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Seiffert, Loskutoff: "Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin." in: The Journal of biological chemistry, Vol. 266, Issue 5, pp. 2824-30, 1991 (PubMed).

Jenne, Stanley: "Molecular cloning of S-protein, a link between complement, coagulation and cell-substrate adhesion." in: The EMBO journal, Vol. 4, Issue 12, pp. 3153-7, 1986 (PubMed).

Sigurdardottir, Wiman: "Identification of a PAI-1 binding site in vitronectin." in: Biochimica et biophysica acta, Vol. 1208, Issue 1, pp. 104-10, 1994 (PubMed).

Hosts (93), (69), (11), (1)
Reactivities (142), (44), (23), (17), (13), (2), (1), (1), (1), (1)
Applications (137), (90), (25), (23), (17), (16), (12), (11), (11), (11), (10), (6), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1)
Conjugates (5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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