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Details for Product No. ABIN652347

Vitronectin (VTN) (N-Term), (AA 65-93) antibody

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Antigen
Synonyms VN, V75, VNT, Vn, AI256434, Aa1018, VTN, DKFZp470F0511, LOC100228142, vtn, zgc:112277
Epitope
»Alternatives N-Term, AA 65-93
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN652347
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 AA from the N-terminal region of human VTN.
Clone RB17843
Isotype Ig
Specificity This VTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72~101 amino acids from the N-terminal region of human VTN.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VTN
Background VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Synonyms: Vitronectin, Serum-spreading factor, S-protein, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B , VTN
Pathways: Focal adhesion, ECM-receptor interaction
Molecular Weight 54,306 Da
Gene ID 7448
UniProt P04004
Research Area Signaling, Cancer
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.34 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Seiffert, Loskutoff: "Evidence that type 1 plasminogen activator inhibitor binds to the somatomedin B domain of vitronectin." in: The Journal of biological chemistry, Vol. 266, Issue 5, pp. 2824-30, 1991 (PubMed).

Jenne, Stanley: "Molecular cloning of S-protein, a link between complement, coagulation and cell-substrate adhesion." in: The EMBO journal, Vol. 4, Issue 12, pp. 3153-7, 1986 (PubMed).

Sigurdardottir, Wiman: "Identification of a PAI-1 binding site in vitronectin." in: Biochimica et biophysica acta, Vol. 1208, Issue 1, pp. 104-10, 1994 (PubMed).

Alternatives for antigen "Vitronectin (VTN)", type "Antibodies"
Hosts (90), (78), (14), (1)
Reactivities (149), (45), (24), (18), (13), (2), (2), (1), (1), (1)
Applications (142), (96), (24), (24), (16), (16), (14), (13), (12), (10), (7), (6), (6), (5), (5), (3), (2), (2), (2), (2), (2), (2), (1), (1)
Conjugates (5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1)
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