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NEK3 (AA 331-361), (Center) antibody

Details for Product No. ABIN652427
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Antigen
Synonyms HSPK36, ATNEK3, NIMA-RELATED KINASE3, NIMA-related kinase 3, T8M17.60, T8M17_60
Epitope
AA 331-361, Center
(8), (7), (6), (6), (4), (2), (2), (1), (1)
Reactivity
Human
(33), (21), (13), (13), (12), (1), (1)
Host
Rabbit
(37), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(31), (19), (10), (8), (4), (4), (3), (2)
Pubmed 3 references available
Quantity 400 µL
Options
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Catalog No. ABIN652427
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This NEK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 AA from the Central region of human NEK3.
Clone RB2961
Isotype Ig
Specificity This NEK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 339~368 amino acids from the center region of human NEK3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. NEK3 is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm.
Synonyms: Serine/threonine-protein kinase Nek3, NimA-related protein kinase 3, HSPK 36
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
anti-NEK3 (AA 331-361), (Center) antibody NEK3 Antibody (K346) (ABIN652427) western blot analysis in CEM cell line lysates (35 µg/lane).This demonstrates the NEK3 antibody detected the NEK3 protein (arrow).
anti-NEK3 (AA 331-361), (Center) antibody (2) Western blot analysis of NEK3 (arrow) using rabbit polyclonal NEK3 Antibody (K346) (ABIN652427). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the NEK3 gene.
Background publications Schultz, Fry, Sütterlin et al.: "Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 5, Issue 6, pp. 625-35, 1994 (PubMed).

Schultz, Nigg: "Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 4, Issue 10, pp. 821-30, 1994 (PubMed).

Kimura, Okano: "Molecular cloning and characterization of the human NIMA-related protein kinase 3 gene (NEK3)." in: Cytogenetics and cell genetics, Vol. 95, Issue 3-4, pp. 177-82, 2002 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN652427
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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