Lymphotoxin-alpha (LTA) (AA 46-72), (Center) antibody

Details for Product No. ABIN652448
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Antigen
Synonyms LT, TNFB, TNFSF1
Epitope
AA 46-72, Center
(4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(112), (30), (26), (17), (14), (4), (2), (2), (2), (1), (1), (1)
Host
Rabbit
(74), (50), (4), (2), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(11), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(86), (70), (22), (21), (17), (12), (12), (11), (10), (9), (8), (4), (4), (3), (3), (3), (1)
Pubmed 1 reference available
Catalog no. ABIN652448
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This LTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-72 AA from the Central region of human LTA.
Clone RB21239
Isotype Ig
Specificity This LTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52~81 amino acids from the Center region of human LTA.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LTA
Background LTA, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.
Synonyms: Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, TNFSF1, TNFB, LTA
Molecular Weight 22297 DA
Gene ID 4049
UniProt P01374
Research Area Neurology
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Lymphotoxin-alpha (LTA) (AA 46-72), (Center) antibody Western blot analysis of LTA Antibody (Center) (ABIN652448) in MDA-MB231 cell line lysates (35 µg/lane). LTA (arrow) was detected using the purified polyclonal antibody.
anti-Lymphotoxin-alpha (LTA) (AA 46-72), (Center) antibody (2) Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with LTA Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-Lymphotoxin-alpha (LTA) (AA 46-72), (Center) antibody (3) Flow cytometric analysis of HepG2 cells using LTA Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Buonaguro, Barillari, Chang et al.: "Effects of the human immunodeficiency virus type 1 Tat protein on the expression of inflammatory cytokines." in: Journal of virology, Vol. 66, Issue 12, pp. 7159-67, 1992 (PubMed).

Hosts (74), (50), (4), (2), (1)
Reactivities (112), (30), (26), (17), (14), (4), (2), (2), (2), (1), (1), (1)
Applications (86), (70), (22), (21), (17), (12), (12), (11), (10), (9), (8), (4), (4), (3), (3), (3), (1)
Conjugates (11), (5), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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