IL8 is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor.
Synonyms: Interleukin-8, IL-8, C-X-C motif chemokine 8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil-activating peptide, MONAP, Emoctakin, MDNCF-a, IL8/NAP1 form I, GCP/IL-8 protein IV, Interleukin-8, IL-8(1-77), MDNCF-b, IL8/NAP1 form II, GCP/IL-8 protein II, (Ala-IL-8)77, IL-8(5-77), IL-8(6-77), Lymphocyte-derived neutrophil-activating factor, LYNAP, Neutrophil-activating factor, NAF, MDNCF-c, IL8/NAP1 form III, GCP/IL-8 protein I, (Ser-IL-8)72, IL-8(7-77), IL8/NAP1 form IV, GCP/IL-8 protein V, IL-8(8-77), IL8/NAP1 form V, GCP/IL-8 protein VI, IL-8(9-77), IL8/NAP1 form VI, GCP/IL-8 protein III , CXCL8, IL8
Pathways: Hepatitis C, Cytokine-cytokine receptor interaction, Pathways in cancer, Chemokine signaling pathway, Toll-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Malaria, Bladder cancer, Rheumatoid arthritis, Epithelial cell signaling in Helicobacter pylori infection, Chagas disease (American trypanosomiasis), Amoebiasis, Shigellosis