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GDNF antibody (N-Term)

GDNF Reactivity: Human FACS, IHC (p) Host: Rabbit Polyclonal RB21995 unconjugated
Catalog No. ABIN652624
  • Target See all GDNF Antibodies
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Binding Specificity
    • 16
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 8-36, N-Term
    Reactivity
    • 79
    • 43
    • 32
    • 16
    • 16
    • 1
    Human
    Host
    • 74
    • 6
    • 4
    • 3
    Rabbit
    Clonality
    • 73
    • 13
    • 1
    Polyclonal
    Conjugate
    • 39
    • 10
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GDNF antibody is un-conjugated
    Application
    • 78
    • 32
    • 26
    • 18
    • 18
    • 13
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This GDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-36 amino acids from the N-terminal region of human GDNF.
    Clone
    RB21995
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GDNF Primary Antibody
  • Application Notes
    IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))
    Alternative Name
    GDNF (GDNF Products)
    Synonyms
    gdnf antibody, GDNF antibody, AI385739 antibody, gdnfa antibody, hfb1-gdnf antibody, ATF1 antibody, ATF2 antibody, HFB1-GDNF antibody, HSCR3 antibody, glial cell derived neurotrophic factor antibody, glial cell derived neurotrophic factor a antibody, glial cell line derived neurotrophic factor antibody, glial cell derived neurotrophic factor L homeolog antibody, Gdnf antibody, gdnfa antibody, GDNF antibody, gdnf.L antibody
    Background
    GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described.
    Molecular Weight
    23720
    Gene ID
    2668
    NCBI Accession
    NP_000505, NP_001177397, NP_001177398, NP_001265027, NP_954701
    UniProt
    P39905
    Pathways
    RTK Signaling, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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