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Lysosomal Protein Transmembrane 4 beta (LAPTM4B) (N-Term) antibody

Antigen

Lysosomal Protein Transmembrane 4 beta (LAPTM4B)
Synonyms LC27, LAPTM4beta, C330023P13Rik
Binding Site
Alternatives

N-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN652720
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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anti-Lysosomal Protein Transmembrane 4 beta (LAPTM4B) (N-Term) antibody

anti-Lysosomal Protein Transmembrane 4 beta (LAPTM4B) (N-Term) antibody (2)

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name LAPTM4B
Gene ID 55353
UniProt NP_060877
Immunogen This LAPTM4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38~68 amino acids from the N-term region of human LAPTM4B.
Isotype Ig
Description Other names: Lysosome-associated transmembrane protein 4-beta, Lysosomal-associated transmembrane protein 4B, LAPTM4B, PSEC0001
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This LAPTM4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38~68 amino acids from the N-term region of human LAPTM4B.
Molecular Weight 35,123 DA
Comments

Background: LAPTM4B belongs to the LAPTM4/LAPTM5 transporter family. It has an active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.

Application Details
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Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Cancer, Cell Structure
Restrictions For Research Use only

Publications
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Product Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Lysosomal Protein Transmembrane 4 beta (LAPTM4B)", type "Antibodies"
Hosts Rabbit (28)
Reactivities Human (27), Mouse (Murine) (24), Rat (Rattus) (23), Cow (Bovine) (2), Cat (Feline) (1), Chicken (1), Dog (Canine) (1), Xenopus laevis (1)
Applications Immunofluorescence (IF) (16), Western Blotting (WB) (13), ELISA (10), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (IHC) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (1), Internal Region (1), N-Term (1)