RGS4 antibody (AA 147-174)

Catalog No. ABIN652827

Product Details anti-RGS4 Antibody

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Binding Specificity: AA 147-174

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS4 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, Pr, Rb, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RGS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the Central region of human RGS4.

Clone: RB21256

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for RGS4

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Alternative Name: RGS4 (RGS4 Products)

Background: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.

Molecular Weight: 23256

Gene ID: 5999

NCBI Accession: NP_001095915, NP_001106851, NP_001106852, NP_005604

UniProt: P49798

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling