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Details for Product No. ABIN652861

Chromobox Homolog 1 (CBX1) (C-Term), (AA 128-155) antibody

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Antigen
Synonyms CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta, Cbx, Cbx-rs2, E430007M08Rik, HP1B, Hp1beta, cbx1, wu:fe14b09, zgc:55739
Epitope
»Alternatives C-Term, AA 128-155
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN652861
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This CBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 AA from the C-terminal region of human CBX1.
Clone RB23535
Isotype Ig
Specificity This CBX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135~164 amino acids from the C-terminal region of human CBX1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CBX1
Background CBX1 is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.
Synonyms: p25beta, HP1Hsbeta, Heterochromatin protein p25, M31, Modifier 1 protein, Heterochromatin protein 1 homolog beta, HP1 beta, Chromobox protein homolog 1, CBX1, CBX
Molecular Weight 21418 DA
Gene ID 10951
UniProt P83916
Research Area Neurology
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Aagaard, Laible, Selenko et al.: "Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31." in: The EMBO journal, Vol. 18, Issue 7, pp. 1923-38, 1999 (PubMed).

Alternatives for antigen "Chromobox Homolog 1 (CBX1)", type "Antibodies"
Hosts (26), (13), (13), (4)
Reactivities (51), (27), (22), (15), (14), (8), (7), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (46), (24), (10), (9), (7), (7), (5), (4), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (4), (2), (2), (1), (1), (1), (1), (1), (1)
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