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Ras Association (RalGDS/AF-6) Domain Family Member 4 (RASSF4) (Center) antibody

Antigen

Ras Association (RalGDS/AF-6) Domain Family Member 4 (RASSF4)

Synonyms AD037, MGC44914, AI586137, 3830411C14Rik, MGC105606, rassf4, MGC84561, ad037, DKFZp469P1033
Binding Site
Alternatives

Center

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN652889
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name RASSF4
Gene ID 83937
UniProt Q9H2L5
Immunogen This RASSF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214~243 amino acids from the Center region of human RASSF4.
Isotype Ig
Description Other names: Ras association domain-containing protein 4, RASSF4, AD037
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This RASSF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214~243 amino acids from the Center region of human RASSF4.
Molecular Weight 36748 DA
Comments

Background: The function of RASSF4 has not yet been determined but it may involve a role in tumor suppression. RASSF4 may act as a KRAS effector protein and may promote apoptosis and cell cycle arrest. Alternative splicing of this gene results in several transcript variants, however, most of the variants have not been fully described.

Application Details

Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Neurology
Restrictions For Research Use only

Publications

Product Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

French, Yang, Cheng et al.: "Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia." in: Blood, Vol. 113, Issue 19, pp. 4512-20, 2009 (PubMed).

Alternatives

Alternatives for antigen "Ras Association (RalGDS/AF-6) Domain Family Member 4 (RASSF4)", type "Antibodies"
Hosts Rabbit (25), Goat (3)
Reactivities Human (25), Mouse (Murine) (21), Rat (Rattus) (20), Dog (Canine) (18), Horse (Equine) (18), Pig (Porcine) (18)
Applications Immunofluorescence (IF) (15), ELISA (11), Western Blotting (WB) (9), Immunohistochemistry (IHC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes Internal Region (2)