Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) (Center) antibody

Antigen: Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)

Synonyms: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1, FLJ26167, CG12215, CG12915, CG33135, dKCNQ, DKCNQ, DmelCG33135, kcnq1, KCNQ1, kqt-3, kv7.1, Kvlqt1, kcnq1-A, KvLQT-1, xkvlqt1, zgc:158384

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN652891

Additional Information

Alternative name: KCNQ1

Gene ID: 3784

UniProt: P51787

Immunogen: This KCNQ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519~549 amino acids from the Center region of human KCNQ1.

Isotype: Ig

Description: Other names: KQT-like 1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, Voltage-gated potassium channel subunit Kv7.1, Potassium voltage-gated channel subfamily KQT member 1, KCNQ1, KCNA8, KCNA9, KVLQT1

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This KCNQ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519~549 amino acids from the Center region of human KCNQ1.

Molecular Weight: 61474 DA

Comments:

Background: KCNQ1 is a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3.

Synonyms: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1, FLJ26167, CG12215, CG12915, CG33135, dKCNQ, DKCNQ, DmelCG33135, kcnq1, KCNQ1, kqt-3, kv7.1, Kvlqt1, kcnq1-A, KvLQT-1, xkvlqt1, zgc:158384

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Restrictions: For Research Use only

Images

Western blot analysis of KCNQ1 Antibody (Center) (ABIN652891) in mouse lung tissue lysates (35ug/lane). KCNQ1 (arrow) was detected using the purified Pab.

KCNQ1 Antibody (Center) (ABIN652891) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Publications

Product: Holm, Gudbjartsson, Arnar et al.: "Several common variants modulate heart rate, PR interval and QRS duration." in: Nature genetics, Vol. 42, Issue 2, pp. 117-22, 2010 (PubMed).