|+1 404 474 4654|
|+1 888 205 9894 (TF)|
TBP-Associated Factor 172 (BTAF1) (C-Term) antibody
|Synonyms||MOT1, TAF172, KIAA0940, TAFII170, MGC138406, TAF(II)170|
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This BTAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1823-1852 amino acids from the C-terminal region of human BTAF1.|
|Description||Other names: TATA-binding protein-associated factor 172,BTAF1,TAF172|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This BTAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1823-1852 amino acids from the C-terminal region of human BTAF1.|
|Molecular Weight||206887 DA|
Background: Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP, MIM 600075) and TBP-associated factors, or TAFs (e.g., TAF2B, MIM 604912), in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is composed of TBP and more than 8 TAFs. However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry~~ 1:50~100 Flow cytometry ~~ 1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Restrictions||For Research Use only|
Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).
Grob, Cruse, Inouye et al.: "Cryo-electron microscopy studies of human TFIID: conformational breathing in the integration of gene regulatory cues." in: Structure (London, England : 1993), Vol. 14, Issue 3, pp. 511-20, 2006 (PubMed).
Koutroubas, Merika, Thanos: "Bypassing the requirements for epigenetic modifications in gene transcription by increasing enhancer strength." in: Molecular and cellular biology, Vol. 28, Issue 3, pp. 926-38, 2008 (PubMed).
|Hosts||Rabbit (5), Mouse (3)|
|Applications||Immunoprecipitation (IP) (6), Western Blotting (WB) (6), ELISA (2), Flow Cytometry (FACS) (2), Immunocytochemistry (ICC) (2), Dot Blot (Dot) (1), Immunoassay (IA) (1), Immunohistochemistry (IHC) (1)|
|Epitopes||AA 1050-1100 (1), AA 1325-1375 (1), AA 75-125 (1), C-Term (1), N-Term (1)|