SKA3 antibody (AA 226-253)

Catalog No. ABIN652928

Product Details anti-SKA3 Antibody

Target: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Binding Specificity: AA 226-253

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SKA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This C13orf3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the Central region of human C13orf3.

Clone: RB23058

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SKA3

Target: SKA3 (Spindle and Kinetochore Associated Complex Subunit 3 (SKA3))

Alternative Name: C13orf3 (SKA3 Products)

Synonyms: C13orf3 antibody, RAMA1 antibody, RGD1307201 antibody, C12H13ORF3 antibody, fc23d11 antibody, si:rp71-68n21.13 antibody, wu:fc23d11 antibody, rama1 antibody, F630043A04Rik antibody, spindle and kinetochore associated complex subunit 3 antibody, spindle and kinetochore associated complex subunit 3 L homeolog antibody, SKA3 antibody, Ska3 antibody, ska3 antibody, ska3.L antibody

Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.

Molecular Weight: 46359

Gene ID: 221150

NCBI Accession: NP_001159489, NP_659498

UniProt: Q8IX90