SPG20 antibody (N-Term)

Catalog No. ABIN652983

Product Details anti-SPG20 Antibody

Target: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Binding Specificity: AA 18-45, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPG20 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SPG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human SPG20.

Clone: RB22531

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SPG20

Target: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Alternative Name: SPG20 (SPG20 Products)

Synonyms: SPARTIN antibody, TAHCCP1 antibody, AI840044 antibody, C79168 antibody, mKIAA0610 antibody, spartin antibody, Spg20 antibody, spg20a antibody, zgc:172059 antibody, spg20b antibody, zgc:153766 antibody, spartin antibody, spastic paraplegia 20, spartin (Troyer syndrome) homolog (human) antibody, spartin a antibody, spartin b antibody, SPART antibody, Spg20 antibody, Spart antibody, sparta antibody, spartb antibody

Background: SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.

Molecular Weight: 72833

Gene ID: 23111

NCBI Accession: NP_001135766, NP_001135767, NP_001135768, NP_055902

UniProt: Q8N0X7

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interactome