|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Minichromosome Maintenance Complex Component 5 (MCM5) (C-Term) antibody
|Synonyms||CDC46, MGC5315, P1-CDC46, Cdc46, Mcmd5, mCD46, mCDC46, AA617332, AI324988, AL033333, mcm5-b, MGC68977, mcm5, MGC97563, 23.m06024|
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
|2 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This MCM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 705~734 amino acids from the C-terminal region of human MCM5.|
|Description||Other names: P1-CDC46, CDC46 homolog, DNA replication licensing factor MCM5, CDC46, MCM5|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This MCM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 705~734 amino acids from the C-terminal region of human MCM5.|
|Molecular Weight||82286 DA|
Background: MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Immunohistochemistry ~~ 1:50~100 Flow cytometry ~~ 1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Stem Cells|
|Restrictions||For Research Use only|
Snyder, Huang, Zhang: "The minichromosome maintenance proteins 2-7 (MCM2-7) are necessary for RNA polymerase II (Pol II)-mediated transcription." in: The Journal of biological chemistry, Vol. 284, Issue 20, pp. 13466-72, 2009 (PubMed).
Saade, Mechold, Kulyyassov et al.: "Analysis of interaction partners of H4 histone by a new proteomics approach." in: Proteomics, Vol. 9, Issue 21, pp. 4934-43, 2009 (PubMed).