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ITGA6 antibody (Integrin, alpha 6) (AA 1082-1110)

Details for Product anti-ITGA6 Antibody No. ABIN653202, Supplier: Log in to see
Antigen
  • 5033401O05Rik
  • AI115430
  • CD49f
  • Cd49f
  • im:6897425
  • inta6
  • itga6
  • ITGA6
  • ITGA6B
  • LOC100221694
  • si:dkey-32o22.1
  • VLA-6
  • wu:fb80g02
Epitope
AA 1082-1110, C-Term
18
14
14
13
9
8
7
6
5
5
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
323
119
38
25
18
17
12
8
6
2
2
2
2
1
1
Host
Rabbit
123
119
107
2
Clonality (Clone)
Polyclonal ()
Conjugate
This ITGA6 antibody is un-conjugated
39
33
22
9
6
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
223
104
92
80
58
50
29
21
11
10
7
5
4
2
2
2
2
1
Supplier
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Immunogen This CD49f antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1082-1110 AA from the C-terminal region of human CD49f.
Clone RB18006
Isotype Ig
Specificity This CD49f antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1089~1118 amino acids from the C-terminal region of human CD49f.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CD49f (ITGA6 Antibody Abstract)
Background The CD49f protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Synonyms: Integrin alpha-6 light chain, Integrin alpha-6 heavy chain, CD_antigen=CD49f, CD49 antigen-like family member F, VLA-6, Integrin alpha-6, ITGA6
Molecular Weight 126633 DA
Gene ID 3655
UniProt P23229
Research Area Stem Cells, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ITGA6 antibody (Integrin, alpha 6) (AA 1082-1110) (ABIN653202) Western blot analysis of CD49f Antibody (C-term) (ABIN653202) in 293 cell line lysate...
Immunohistochemistry (IHC) image for anti-ITGA6 antibody (Integrin, alpha 6) (AA 1082-1110) (ABIN653202) Formalin-fixed and paraffin-embedded human brain tissue reacted with CD49f Antibody (...
Flow Cytometry (FACS) image for anti-ITGA6 antibody (Integrin, alpha 6) (AA 1082-1110) (ABIN653202) CD49f Antibody (C-term) (ABIN653202) flow cytometry analysis of 293 cells (bottom his...
Background publications Kim, Kim, Soung, Shaw, Chung: "Integrin (alpha6beta4) signals through Src to increase expression of S100A4, a metastasis-promoting factor: implications for cancer cell invasion." in: Molecular cancer research : MCR, Vol. 7, Issue 10, pp. 1605-12, 2009 (PubMed).

Eeles, Kote-Jarai, Al Olama, Giles, Guy, Severi, Muir, Hopper, Henderson, Haiman, Schleutker, Hamdy, Neal, Donovan, Stanford, Ostrander, Ingles, John, Thibodeau, Schaid, Park, Spurdle, Clements et al.: "Identification of seven new prostate cancer susceptibility loci through a genome-wide association study." in: Nature genetics, Vol. 41, Issue 10, pp. 1116-21, 2009 (PubMed).