IK Cytokine, Down-Regulator of HLA II (IK) (N-Term) antibody

Antigen: IK Cytokine, Down-Regulator of HLA II (IK)

Synonyms: RED, CSA2, MGC59741, zgc:56500, wu:fb54c03, IK, MGC139745, DKFZp459A1710, DKFZp459P1413, LOC100220119

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN653489

Additional Information

Alternative name: IK

Gene ID: 3550

UniProt: Q13123

Immunogen: This IK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86~115 amino acids from the N-terminal region of human IK.

Isotype: Ig

Description: Other names: Cytokine IK, IK factor, Protein RER, Protein Red, RER, RED, IK

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This IK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86~115 amino acids from the N-terminal region of human IK.

Molecular Weight: 65630 DA

Comments:

Background: IK was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Signaling, Protein Modifications, Neurology

Restrictions: For Research Use only

Images

Western blot analysis of IK Antibody (N-termianl) (ABIN653489) in A375 cell line lysates (35ug/lane). IK (arrow) was detected using the purified Pab.

Publications

Product: Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).