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Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) (AA 10-38), (N-Term) antibody

Details for Product No. ABIN653748, Supplier: Log in to see
Antigen
  • crtl1
  • hapln1
  • wu:fc26f11
  • wu:fc37g04
  • wu:fc50e12
  • wu:fc55h01
  • CRTL1
  • LP
  • BB099155
  • CLP
  • Crtl1
  • Crtl1l
  • LP-1
  • CTRL1
Epitope
AA 10-38, N-Term
20
16
4
2
1
Reactivity
Human
44
17
17
Host
Rabbit
41
3
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
32
17
16
14
11
5
Supplier
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Immunogen This HAPLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 AA from the N-terminal region of human HAPLN1.
Clone RB24639
Isotype Ig
Specificity This HAPLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17~46 amino acids from the N-terminal region of human HAPLN1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HAPLN1 (HAPLN1 Antibody Abstract)
Background HAPLN1 belongs to the HAPLN family. It contains 1 Ig like V type (immunoglobulin like) domain and 2 Link domains. This protein stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
Synonyms: Cartilage-linking protein 1, Cartilage-link protein, Proteoglycan link protein, Hyaluronan and proteoglycan link protein 1,CRTL1, HAPLN1
Molecular Weight 40166 Da
Gene ID 1404
UniProt P10915
Research Area Cancer, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) (AA 10-38), (N-Term) antibody (ABIN653748) HAPLN1 Antibody (N-term) (ABIN653748) western blot analysis in MCF-7,Jurkat,HepG2 cel...
Immunohistochemistry (IHC) image for anti-Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) (AA 10-38), (N-Term) antibody (ABIN653748) HAPLN1 Antibody (N-term) (ABIN653748) IHC analysis in formalin fixed and paraffin emb...
Flow Cytometry (FACS) image for anti-Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) (AA 10-38), (N-Term) antibody (ABIN653748) HAPLN1 Antibody (N-term) (ABIN653748) flow cytometric analysis of MCF-7 cells (right ...
Product cited in: Kobayashi, Nagashio, Ryuge et al.: "Acquisition of useful sero-diagnostic autoantibodies using the same patients'sera and tumor tissues." in: Biomedical research (Tokyo, Japan), Vol. 35, Issue 2, pp. 133-43, 2014 (PubMed).

Background publications Wheeler, Metter, Tanaka et al.: "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000685, 2009 (PubMed).

Seyfried, McVey, Almond et al.: "Expression and purification of functionally active hyaluronan-binding domains from human cartilage link protein, aggrecan and versican: formation of ternary complexes with defined hyaluronan ..." in: The Journal of biological chemistry, Vol. 280, Issue 7, pp. 5435-48, 2005 (PubMed).