Cdk5 and Abl Enzyme Substrate 1 (CABLES1) (C-Term) antibody

Antigen: Cdk5 and Abl Enzyme Substrate 1 (CABLES1)

Synonyms: ik3-1, Cables, IK3-1, CABLES, HsT2563, FLJ35924, CABLES1, cables1

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Certificates: ISO 9001:2008

Catalog no.: ABIN653785

Additional Information

Alternative name: CABLES1

Gene ID: 91768

UniProt: Q8TDN4

Immunogen: This CABLES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576~606 amino acids from the C-terminal region of human CABLES1.

Isotype: Ig

Description: Other names: Interactor with CDK3 1, Ik3-1, CDK5 and ABL1 enzyme substrate 1,CABLES, CABLES1

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This CABLES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576~606 amino acids from the C-terminal region of human CABLES1.

Molecular Weight: 67599 DA

Comments:

Background: CABLES1 is a cyclin-dependent kinase (CDK)-binding protein that plays a role in proliferation and/or differentiation.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Protein Modifications, Cell Cycle, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of CABLES1 Antibody (C-term) (ABIN653785) in Jurkat cell line lysates (35ug/lane).CABLES1 (arrow) was detected using the purified Pab.

Western blot analysis of CABLES1 Antibody (C-term) (ABIN653785) in mouse heart tissue lysates (35ug/lane).CABLES1 (arrow) was detected using the purified Pab.

CABLES1 Antibody (C-term) (ABIN653785) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CABLES1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Gudbjartsson, Walters, Thorleifsson et al.: "Many sequence variants affecting diversity of adult human height." in: Nature genetics, Vol. 40, Issue 5, pp. 609-15, 2008 (PubMed).

Caporaso, Gu, Chatterjee et al.: "Genome-wide and candidate gene association study of cigarette smoking behaviors." in: PLoS ONE, Vol. 4, Issue 2, pp. e4653, 2009 (PubMed).