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Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1) (AA 665-692), (C-Term) antibody

Details for Product No. ABIN653787, Supplier: Log in to see
Antigen
  • 9330160G10Rik
  • D7Wsu87e
  • Gm1956
  • Trabid
  • TRABID
  • trabid
  • zgc:154177
  • zranb1
Epitope
AA 665-692, C-Term
32
9
8
Reactivity
Human, Mouse (Murine)
35
6
4
3
3
1
1
1
Host
Rabbit
21
15
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
3
3
3
3
3
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
35
25
15
2
1
Supplier
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Immunogen This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 AA from the C-terminal region of human ZRANB1.
Clone RB23203
Isotype Ig
Specificity This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 672~701 amino acids from the C-terminal region of human ZRANB1.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ZRANB1 (ZRANB1 Antibody Abstract)
Background ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
Synonyms: hTrabid, Zinc finger Ran-binding domain-containing protein 1, Ubiquitin thioesterase ZRANB1,TRABID, ZRANB1
Molecular Weight 80967 DA
Gene ID 54764
UniProt Q9UGI0
Research Area Signaling, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1) (AA 665-692), (C-Term) antibody (ABIN653787) Western blot analysis of ZRANB1 Antibody (C-term) (ABIN653787) in K562 cell line lysa...
Western Blotting (WB) image for anti-Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1) (AA 665-692), (C-Term) antibody (ABIN653787) Western blot analysis of ZRANB1 Antibody (C-term) (ABIN653787) in mouse cerebellum ti...
Immunohistochemistry (IHC) image for anti-Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1) (AA 665-692), (C-Term) antibody (ABIN653787) ZRANB1 Antibody (C-term) (ABIN653787) IHC analysis in formalin fixed and paraffin emb...
Background publications Tran, Hamada, Schwarz-Romond, Bienz: "Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains." in: Genes & development, Vol. 22, Issue 4, pp. 528-42, 2008