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WASP antibody (AA 116-144)

WAS Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB23643 unconjugated
Catalog No. ABIN653830
  • Target See all WASP (WAS) Antibodies
    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
    Binding Specificity
    • 15
    • 14
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-144
    Reactivity
    • 86
    • 54
    • 19
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 83
    • 3
    • 1
    Rabbit
    Clonality
    • 84
    • 3
    Polyclonal
    Conjugate
    • 33
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This WASP antibody is un-conjugated
    Application
    • 61
    • 37
    • 25
    • 15
    • 13
    • 13
    • 8
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This WAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human WAS.
    Clone
    RB23643
    Isotype
    Ig Fraction
    Top Product
    Discover our top product WAS Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
    Alternative Name
    WAS (WAS Products)
    Synonyms
    IMD2 antibody, SCNX antibody, THC antibody, THC1 antibody, WASP antibody, U42471 antibody, WASp antibody, Wasp antibody, imd2 antibody, thc antibody, thc1 antibody, was antibody, wasp antibody, wu:fk81c08 antibody, zgc:64164 antibody, Wiskott-Aldrich syndrome antibody, neural Wiskott-Aldrich syndrome protein antibody, wiskott-aldrich syndrome protein antibody, Wiskott-Aldrich syndrome L homeolog antibody, Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b antibody, WAS antibody, LOC5578888 antibody, CpipJ_CPIJ006699 antibody, Was antibody, was.L antibody, wasb antibody
    Background
    The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients.
    Molecular Weight
    52913
    Gene ID
    7454
    NCBI Accession
    NP_000368
    UniProt
    P42768
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