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Details for Product No. ABIN653888

Histone H3 (HTR12) (Lys9) antibody

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Antigen
Synonyms H3/i, H3FI, h3, Hist1h3f, hist2h3c, CENH3, CENTROMERIC HISTONE H3, F6F3.17, F6F3_17
Epitope
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 4 references available
Catalog no. ABIN653888
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This Histone H3-K9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the K9 region of human histone H3.
Clone RB08332
Isotype Ig
Specificity This Histone H3-K9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the K9 region of human histone H3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Histone H3
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene for histone H3-MeK9 is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Synonyms: Histone H3, PP781, H3F3, H3.3A, H3F3A
Molecular Weight 15273 DA
Gene ID 3021
UniProt P84243
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.32 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Loyola, Bonaldi, Roche et al.: "PTMs on H3 variants before chromatin assembly potentiate their final epigenetic state." in: Molecular cell, Vol. 24, Issue 2, pp. 309-16, 2006 (PubMed).

Morris, Rao, Garcia et al.: "Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification." in: The Journal of biological chemistry, Vol. 282, Issue 10, pp. 7632-40, 2007 (PubMed).

Garcia, Hake, Diaz et al.: "Organismal differences in post-translational modifications in histones H3 and H4." in: The Journal of biological chemistry, Vol. 282, Issue 10, pp. 7641-55, 2007 (PubMed).

Teng, Ballim, Mowla et al.: "Phosphorylation of histone H3 by protein kinase C signaling plays a critical role in the regulation of the developmentally important TBX2 gene." in: The Journal of biological chemistry, Vol. 284, Issue 39, pp. 26368-76, 2009 (PubMed).

Alternatives for antigen "Histone H3 (HTR12)", type "Antibodies"
Hosts (455), (34), (8), (2)
Reactivities (462), (303), (300), (174), (156), (12), (8), (8), (5), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Applications (316), (188), (159), (128), (95), (83), (51), (45), (39), (24), (13), (11), (1)
Conjugates (18), (17), (17), (16), (16), (16), (16), (16), (16), (16), (16), (2), (1)
Epitopes (40), (35), (30), (29), (25), (23), (21), (18), (17), (16), (16), (14), (14), (14), (11), (10), (9), (7), (7), (6), (6), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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