Tectonic Family Member 3 (TCTN3) (C-Term) antibody

Antigen: Tectonic Family Member 3 (TCTN3)

Synonyms: RGD1305166, TECT3, C10orf61, DKFZp564D116, Tect3, AI197391, 4930521E07Rik, CVAL, VALOP

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Certificates: ISO 9001:2008

Catalog no.: ABIN653950

Additional Information

Alternative name: TCTN3

Gene ID: 26123

UniProt: Q6NUS6

Immunogen: This TCTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542~571 amino acids from the C-terminal region of human TCTN3.

Isotype: Ig

Description: Other names: Tectonic-3,UNQ1881/PRO4324, PSEC0041, TECT3, C10orf61, TCTN3

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This TCTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542~571 amino acids from the C-terminal region of human TCTN3.

Molecular Weight: 66157 DA

Comments:

Background: TCTN3 may be involved in apoptosis regulation.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Apoptosis/Necrosis, Cell Signaling, Cell Structure, Protein Modifications

Restrictions: For Research Use only

Images

Western blot analysis of TCTN3 Antibody (C-term) (ABIN653950) in MDA-MB231 cell line lysates (35ug/lane). TCTN3 (arrow) was detected using the purified Pab.

TCTN3 Antibody (C-term) (ABIN653950) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TCTN3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Reiter, Skarnes: "Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition." in: Genes & development, Vol. 20, Issue 1, pp. 22-7, 2006 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).