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Angiopoietin 2 antibody (C-Term)

ANGPT2 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB17789 unconjugated
Catalog No. ABIN654062
  • Target See all Angiopoietin 2 (ANGPT2) Antibodies
    Angiopoietin 2 (ANGPT2)
    Binding Specificity
    • 15
    • 9
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 404-432, C-Term
    Reactivity
    • 75
    • 36
    • 26
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 77
    • 10
    • 4
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 68
    • 26
    Polyclonal
    Conjugate
    • 48
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiopoietin 2 antibody is un-conjugated
    Application
    • 64
    • 32
    • 32
    • 13
    • 13
    • 11
    • 10
    • 10
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ANGPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human ANGPT2.
    Clone
    RB17789
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ANGPT2 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100. FC: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Alamo, Gallardo, Di Nicolantonio, Pavón, Casanova, Trias, Mangues, Lopez-Pousa, Villaverde, Vázquez, Bardelli, Céspedes, Mangues: "Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 2, pp. 464-76, (2015) (PubMed).

    Alamo, Gallardo, Pavón, Casanova, Trias, Mangues, Vázquez, Villaverde, Mangues, Céspedes: "Subcutaneous preconditioning increases invasion and metastatic dissemination in mouse colorectal cancer models." in: Disease models & mechanisms, Vol. 7, Issue 3, pp. 387-96, (2014) (PubMed).

  • Target
    Angiopoietin 2 (ANGPT2)
    Alternative Name
    ANGPT2 (ANGPT2 Products)
    Synonyms
    AGPT2 antibody, ANG2 antibody, Agpt2 antibody, Ang-2 antibody, Ang2 antibody, ang2 antibody, angpt2 antibody, ANGIOPOIETIN-2 antibody, ANG-2 antibody, ANGPT2 antibody, Angrp antibody, Rnase5b antibody, ANG3 antibody, C11orf2 antibody, C11orf3 antibody, FFR antibody, angiopoietin 2 antibody, angiopoietin 2b antibody, angiogenin, ribonuclease A family, member 2 antibody, VPS51, GARP complex subunit antibody, ANGPT2 antibody, Angpt2 antibody, angpt2b antibody, Ang2 antibody, VPS51 antibody
    Background
    The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
    Molecular Weight
    56919
    Gene ID
    285
    NCBI Accession
    NP_001112359, NP_001112360, NP_001138
    UniProt
    O15123
    Pathways
    RTK Signaling
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