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ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody

Details for Product No. ABIN654102, Supplier: Log in to see
Antigen
  • EST182763
  • MRP7
  • SIMRP7
  • Mrp7
  • mFLJ00002
  • 6230418K12Rik
  • Abcc10
  • C130009K11Rik
  • OM-1
  • Om1
  • Ranbp8
Epitope
AA 767-793, Center
28
16
10
6
3
3
2
1
1
1
Reactivity
Human
76
14
14
1
Host
Rabbit
54
14
5
4
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
50
39
23
16
11
7
3
3
3
1
1
1
Supplier
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Immunogen This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 767-793 AA from the Central region of human ABCC10.
Clone RB22383
Isotype Ig
Specificity This ABCC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-801 amino acids from the Central region of human ABCC10.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ABCC10 (ABCC10 Antibody Abstract)
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: Multidrug resistance-associated protein 7,ABCC10,MRP7, SIMRP7
Molecular Weight 161629 DA
Gene ID 89845
NCBI Accession NP_258261
UniProt Q5T3U5
Research Area Phospho-specific antibodies, Cell Structure, Protein Modifications, Signaling, Chromatin
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody (ABIN654102) ABCC10 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane...
Immunohistochemistry (IHC) image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody (ABIN654102) ABCC10 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffi...
Flow Cytometry (FACS) image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 10 (ABCC10) (AA 767-793), (Center) antibody (ABIN654102) ABCC10 Antibody (Center) flow cytometric analysis of HepG2 cells (right histogram) c...
Background publications Zhou, Hopper-Borge, Shen et al.: "Cepharanthine is a potent reversal agent for MRP7(ABCC10)-mediated multidrug resistance." in: Biochemical pharmacology, Vol. 77, Issue 6, pp. 993-1001, 2009 (PubMed).