Acetyl-CoA Acyltransferase 1 (ACAA1) (N-Term) antibody

Antigen: Acetyl-CoA Acyltransferase 1 (ACAA1)

Synonyms: ACAA, THIO, PTHIO, PTL, Acaa, Acaa1, MGC7090, D9Ertd25e, MGC64556, zgc:92385, MGC128200, acaa, thio, pthio, MGC147499, T2, MAT, ACAT, THIL, SOAT, STAT, ACACT, ACAT1, RP11-215I23.2, ald, Acact, ACAT-1, AW550831, 8430426K15Rik, RATACAL, Acat-1, Acat, 6330585C21Rik, fd16h07, fd20g06, zgc:86832, wu:fd16h07, wu:fd20g06, MGC137917, MGC107795, acat1

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN654105

Additional Information

Alternative name: ACAA1

Gene ID: 30

UniProt: NP_001598.1, P09110, NP_001123882.1

Immunogen: This ACAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human ACAA1.

Isotype: Ig

Description: Other names: 3-ketoacyl-CoA thiolase, peroxisomal,ACAA1,ACAA, PTHIO

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This ACAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human ACAA1.

Molecular Weight: 44292 DA

Comments:

Background: This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants.

Synonyms: ACAA, THIO, PTHIO, PTL, Acaa, Acaa1, MGC7090, D9Ertd25e, MGC64556, zgc:92385, MGC128200, acaa, thio, pthio, MGC147499, T2, MAT, ACAT, THIL, SOAT, STAT, ACACT, ACAT1, RP11-215I23.2, ald, Acact, ACAT-1, AW550831, 8430426K15Rik, RATACAL, Acat-1, Acat, 6330585C21Rik, fd16h07, fd20g06, zgc:86832, wu:fd16h07, wu:fd20g06, MGC137917, MGC107795, acat1

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Signaling, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Metabolism, Cell Structure

Restrictions: For Research Use only

Images

ACAA1 Antibody (N-term) (ABIN654105) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ACAA1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).