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Interferon Related Developmental Regulator 1 (IFRD1) (Center) antibody
Alternatives Western Blotting (WB), ELISA
|4 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|UniProt||O00458, NP_001007246.1, NP_001541.2|
|Immunogen||This IFRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-360 amino acids from the Central region of human IFRD1.|
|Description||Other names: Interferon-related developmental regulator 1,IFRD1,|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This IFRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-360 amino acids from the Central region of human IFRD1.|
|Molecular Weight||50269 DA|
Background: This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Phospho-specific antibodies, Protein Modifications, Cell Cycle, Cell Structure|
|Restrictions||For Research Use only|
Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).
Gu, Harley, Henderson et al.: "Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease." in: Nature, Vol. 458, Issue 7241, pp. 1039-42, 2009 (PubMed).
Brkanac, Spencer, Shendure et al.: "IFRD1 is a candidate gene for SMNA on chromosome 7q22-q23." in: American journal of human genetics, Vol. 84, Issue 5, pp. 692-7, 2009 (PubMed).
Zhao, Datta, Mandal et al.: "Stress-sensitive regulation of IFRD1 mRNA decay is mediated by an upstream open reading frame." in: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 8552-62, 2010 (PubMed).