Olfactory Receptor, Family 10, Subfamily A, Member 3 (OR10A3) (C-Term) antibody

Antigen: Olfactory Receptor, Family 10, Subfamily A, Member 3 (OR10A3)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN654326

Additional Information

Alternative name: OR10A3

Gene ID: 26496

UniProt: P58181, NP_001003745.1

Immunogen: This OR10A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-280 amino acids from the C-terminal region of human OR10A3.

Isotype: Ig

Description: Other names: Olfactory receptor 10A3,OR10A3,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This OR10A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-280 amino acids from the C-terminal region of human OR10A3.

Molecular Weight: 35535 DA

Comments:

Background: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

OR10A3 Antibody (C-term) (ABIN654326) western blot analysis in mouse cerebellum tissue lysates (35ug/lane). This demonstrates the OR10A3 antibody detected the OR10A3 protein (arrow).

Publications

Product: Parmentier, Libert, Schurmans et al.: "Expression of members of the putative olfactory receptor gene family in mammalian germ cells." in: Nature, Vol. 355, Issue 6359, pp. 453-5, 1992 (PubMed).

Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Malnic, Godfrey, Buck: "The human olfactory receptor gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 8, pp. 2584-9, 2004 (PubMed).

Taylor, Noguchi, Totoki et al.: "Human chromosome 11 DNA sequence and analysis including novel gene identification." in: Nature, Vol. 440, Issue 7083, pp. 497-500, 2006 (PubMed).