Olfactory Receptor, Family 13, Subfamily C, Member 8 (OR13C8) (C-Term) antibody

Antigen: Olfactory Receptor, Family 13, Subfamily C, Member 8 (OR13C8)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN654378

Additional Information

Alternative name: OR13C8

Gene ID: 138802

UniProt: Q8NGS7, NP_001004483.1

Immunogen: This OR13C8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the C-terminal region of human OR13C8.

Isotype: Ig

Description: Other names: Olfactory receptor 13C8,OR13C8,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This OR13C8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the C-terminal region of human OR13C8.

Molecular Weight: 35294 DA

Comments:

Background: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

OR13C8 antibody (C-term) (ABIN654378) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the OR13C8 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Fuchs, Malecova, Linhart et al.: "DEFOG: a practical scheme for deciphering families of genes." in: Genomics, Vol. 80, Issue 3, pp. 295-302, 2002 (PubMed).

Hoppe, Breer, Strotmann: "Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human." in: Genomics, Vol. 82, Issue 3, pp. 355-64, 2003 (PubMed).

Malnic, Godfrey, Buck: "The human olfactory receptor gene family." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 8, pp. 2584-9, 2004 (PubMed).

Humphray, Oliver, Hunt et al.: "DNA sequence and analysis of human chromosome 9." in: Nature, Vol. 429, Issue 6990, pp. 369-74, 2004 (PubMed).