S6A12 (N-Term), (AA 9-38) antibody

Details for Product No. ABIN654460
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Antigen
Epitope
N-Term, AA 9-38
(1), (1)
Reactivity
Human
(1)
Host
Rabbit
(1)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Flow Cytometry (FACS)
(1), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN654460
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Immunogen This S6A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 AA from the N-terminal region of human S6A12.
Clone RB24381
Isotype Ig
Specificity This S6A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human S6A12.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Synonyms: SLC6A12,Sodium- and chloride-dependent betaine transporter,
Molecular Weight 69368 DA
Gene ID 6539
NCBI Accession NP_001116319, NP_003035, NP_001116320
UniProt P48065
Research Area Cell Structure, Protein Modifications, Neurology
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-S6A12 (N-Term), (AA 9-38) antibody S6A12 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the S6A12 antibody detected the S6A12 protein (arrow).
anti-S6A12 (N-Term), (AA 9-38) antibody (2) S6A12 Antibody (N-term) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Köttgen, Pattaro, Böger et al.: "New loci associated with kidney function and chronic kidney disease...." in: Nature genetics, Vol. 42, Issue 5, pp. 376-84, 2010 (PubMed).

Pasaje, Kim, Park et al.: "Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population." in: Annals of human genetics, Vol. 74, Issue 4, pp. 326-34, 2010 (PubMed).

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