Complement Component 5a Receptor 1 (C5AR1) (AA 175-201), (Center) antibody

Details for Product No. ABIN654658
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Antigen
Epitope
AA 175-201, Center
(13), (8), (8), (7), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(99), (44), (30), (19), (17), (17), (17), (5), (2)
Host
Rabbit
(58), (46), (45), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(15), (8), (8), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(108), (52), (38), (31), (24), (14), (14), (10), (7), (6), (3), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN654658
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Immunogen This C5AR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-201 AA from the Central region of human C5AR1.
Clone RB24276
Isotype Ig
Specificity This C5AR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the Central region of human C5AR1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name C5AR1
Background Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
Synonyms: C5a anaphylatoxin chemotactic receptor,C5AR1,C5AR, C5R1
Molecular Weight 39336 DA
Gene ID 728
NCBI Accession NP_001727
UniProt P21730
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Complement Component 5a Receptor 1 (C5AR1) (AA 175-201), (Center) antibody C5AR1 Antibody (Center) (ABIN654658) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the C5AR1 antibody detected the C5AR1 protein (arrow).
Background publications Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Marc, Kristan, Rozman et al.: "Complement factor C5a in acute exacerbation of Chronic Obstructive Pulmonary Disease." in: Scandinavian journal of immunology, Vol. 71, Issue 5, pp. 386-91, 2010 (PubMed).

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