Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae) (VPS52) (C-Term), (AA 610-637) antibody

Details for Product No. ABIN654879
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Antigen
Synonyms ARE1, RP5-1033B10, SAC2, SACM2L, dJ1033B10.5, Are1, Sacm2l, D130068D18, D430041K17Rik
Epitope
C-Term, AA 610-637
(2), (1), (1), (1), (1)
Reactivity
Human
(8), (2), (2)
Host
Rabbit
(8), (1)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
(9), (4), (3), (2), (2), (2), (1), (1)
Pubmed 4 references available
Catalog no. ABIN654879
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This VPS52 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 610-637 AA from the C-terminal region of human VPS52.
Clone RB25452
Isotype Ig
Specificity This VPS52 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the C-terminal region of human VPS52.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VPS52
Background This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.
Synonyms: Vacuolar protein sorting-associated protein 52 homolog,VPS52,SACM2L
Molecular Weight 82221 DA
Gene ID 6293
UniProt Q8N1B4, NP_072047.4
Research Area Cell Structure, Signaling, Chromatin
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae) (VPS52) (C-Term), (AA 610-637) antibody Confocal immunofluorescent analysis of VPS52 Antibody (C-term)(ABIN654879) with MCF-7 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Background publications Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6...." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Liewen, Meinhold-Heerlein, Oliveira et al.: "Characterization of the human GARP (Golgi associated retrograde protein) complex." in: Experimental cell research, Vol. 306, Issue 1, pp. 24-34, 2005 (PubMed).

Pérez-Victoria, Mardones, Bonifacino: "Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes." in: Molecular biology of the cell, Vol. 19, Issue 6, pp. 2350-62, 2008 (PubMed).

Barcellos, May, Ramsay et al.: "High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000696, 2009 (PubMed).

Hosts (8), (1)
Reactivities (8), (2), (2)
Applications (9), (4), (3), (2), (2), (2), (1), (1)
Epitopes (2), (1), (1), (1), (1)
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