NFE2L1 antibody (Nuclear Factor (erythroid-Derived 2)-Like 1) (AA 709-738)

Details for Product anti-NFE2L1 Antibody No. ABIN654881, Supplier: Log in to see
Antigen
  • NRF1
  • LCR-F1
  • TCF11
  • AA408798
  • AW212678
  • Lcrf1
  • TCF-11
  • nuclear factor (erythroid-derived 2)-like 1
  • nuclear factor, erythroid 2-like 1
  • nuclear factor, erythroid derived 2,-like 1
  • NFE2L1
  • Nfe2l1
Epitope
AA 709-738, C-Term
14
9
9
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
44
26
13
8
7
7
3
3
2
1
1
Host
Rabbit
38
6
Clonality (Clone)
Polyclonal ()
Conjugate
This NFE2L1 antibody is un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
43
23
4
1
1
1
1
1
Options
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Immunogen This NFE2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 709-738 AA from the C-terminal region of human NFE2L1.
Clone RB27999
Isotype Ig
Specificity This NFE2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 712-742 amino acids from the C-terminal region of human NFE2L1.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NFE2L1 (NFE2L1 Antibody Abstract)
Background This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1.
Synonyms: Nuclear factor erythroid 2-related factor 1,NFE2L1,HBZ17, NRF1, TCF11
Molecular Weight 84704 DA
Gene ID 4779
NCBI Accession NP_003195
UniProt Q14494
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-NFE2L1 antibody (Nuclear Factor (erythroid-Derived 2)-Like 1) (AA 709-738) (ABIN654881) NFE2L1 Antibody (C-term) (ABIN654881) western blot analysis in mouse lung tissue lysa...
Background publications Steffen, Seeger, Koch, Krüger: "Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop." in: Molecular cell, Vol. 40, Issue 1, pp. 147-58, 2010 (PubMed).

Radhakrishnan, Lee, Young, Beskow, Chan, Deshaies: "Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells." in: Molecular cell, Vol. 38, Issue 1, pp. 17-28, 2010 (PubMed).

Wang, Kwok, Chan: "The p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcription." in: The Journal of biological chemistry, Vol. 282, Issue 34, pp. 24670-8, 2007 (PubMed).

Newman, Keating: "Comprehensive identification of human bZIP interactions with coiled-coil arrays." in: Science (New York, N.Y.), Vol. 300, Issue 5628, pp. 2097-101, 2003 (PubMed).