ZC12A (AA 331-358), (Center) antibody

Details for Product No. ABIN654931
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Antigen
Epitope
AA 331-358, Center
(1)
Reactivity
Human
(1)
Host
Rabbit
(1)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(1), (1), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN654931
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Immunogen This ZC12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-358 AA from the Central region of human ZC12A.
Clone RB24811
Isotype Ig
Specificity This ZC12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-358 amino acids from the Central region of human ZC12A.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background ZC3H12A is an MCP1 (CCL2, MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.
Synonyms: Ribonuclease ZC3H12A,ZC3H12A,MCPIP, MCPIP1
Molecular Weight 65699 DA
Gene ID 80149
NCBI Accession NP_079355
UniProt Q5D1E8
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-ZC12A (AA 331-358), (Center) antibody ZC12A antibody (Center) (ABIN654931) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining
Background publications Liang, Wang, Azfer et al.: "A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages." in: The Journal of biological chemistry, Vol. 283, Issue 10, pp. 6337-46, 2008 (PubMed).

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