PPM1L antibody (C-Term)

Catalog No. ABIN654954

Product Details anti-PPM1L Antibody

Target: PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))

Binding Specificity: AA 215-244, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PPM1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human PPM1L.

Clone: RB25416

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PPM1L

Target: PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))

Alternative Name: PPM1L (PPM1L Products)

Synonyms: 3222401G13 antibody, 5930404J21Rik antibody, AI481720 antibody, AW045850 antibody, PP2C antibody, PP2Cepsilon antibody, Pp2ce antibody, Ppp2ce antibody, mKIAA4175 antibody, PP2C-epsilon antibody, PP2CE antibody, PPM1-LIKE antibody, ppm1l antibody, zgc:153235 antibody, zgc:154091 antibody, protein phosphatase 1 (formerly 2C)-like antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1L antibody, protein phosphatase, Mg2+/Mn2+ dependent 1L antibody, protein phosphatase, Mg2+/Mn2+ dependent 1L L homeolog antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Lb antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1La antibody, Ppm1l antibody, PPM1L antibody, ppm1l.L antibody, ppm1lb antibody, ppm1la antibody

Background: PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2Cs regulate stress-activated protein kinase (SAPK, see MIM 601158) signaling cascades that respond to extracellular stimuli (Jin et al., 2004 [PubMed 15560375]).

Molecular Weight: 41053

Gene ID: 151742

NCBI Accession: NP_640338

UniProt: Q5SGD2