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Intercellular Adhesion Molecule 2 (ICAM2) (AA 191-218), (Center) antibody

Details for Product No. ABIN655000, Supplier: Log in to see
Antigen
  • ICAM2
  • CD102
  • Icam-2
  • Ly-60
Epitope
AA 191-218, Center
20
18
13
12
5
5
3
3
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
160
119
22
Host
Rabbit
90
87
85
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
42
28
26
5
5
3
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
182
85
77
56
51
32
24
15
11
6
4
4
4
3
3
2
2
1
1
1
Supplier
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Immunogen This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 AA from the Central region of human ICAM2.
Clone RB28558
Isotype Ig
Specificity This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ICAM2 (ICAM2 Antibody Abstract)
Background The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Synonyms: Intercellular adhesion molecule 2,ICAM2,
Molecular Weight 30654 DA
Gene ID 3384
NCBI Accession NP_001093258, NP_001093257, NP_001093256, NP_000864, NP_001093259
UniProt P13598
Research Area Cell Signaling, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.48 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Intercellular Adhesion Molecule 2 (ICAM2) (AA 191-218), (Center) antibody (ABIN655000) ICAM2 Antibody (Center) (ABIN655000) western blot analysis in HepG2 cell line lysates...
Background publications Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Sato, Azuma, Higai et al.: "Altered expression of glycoproteins on the cell surface of Jurkat cells during etoposide-induced apoptosis: shedding and intracellular translocation of glycoproteins." in: Biochimica et biophysica acta, Vol. 1790, Issue 10, pp. 1198-205, 2009 (PubMed).