Prolyl-tRNA Synthetase 2, Mitochondrial (Putative) (PARS2) (C-Term) antibody

Antigen: Prolyl-tRNA Synthetase 2, Mitochondrial (Putative) (PARS2)

Synonyms: MGC14416, MGC19467, MT-PRORS, DKFZp727A071, BC027073, MGC47008, RP23-97O7.3, RGD1305345, fc83e06, zgc:77163, wu:fc83e06, MGC53152

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655042

Additional Information

Alternative name: PARS2

Gene ID: 25973

UniProt: Q7L3T8, NP_689481.2

Immunogen: This PARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-424 amino acids from the C-terminal region of human PARS2.

Isotype: Ig

Description: Other names: Probable prolyl-tRNA synthetase, mitochondrial,PARS2,

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This PARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 397-424 amino acids from the C-terminal region of human PARS2.

Molecular Weight: 53263 DA

Comments:

Background: Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca

Research Area: Translation Factors, Cell Signaling, Chromatin, Signaling, Cell Structure

Restrictions: For Research Use only

Images

PARS2 Antibody (C-term) (ABIN655042) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PARS2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Bonnefond, Fender, Rudinger-Thirion et al.: "Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS." in: Biochemistry, Vol. 44, Issue 12, pp. 4805-16, 2005 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).