You are viewing an incomplete version of our website. Please click to reload the website as full version.

Inhibin, beta A (INHBA) (AA 85-112), (N-Term) antibody

Details for Product No. ABIN655078, Supplier: Log in to see
Antigen
  • actba
  • inhba
  • inhbaa-001
  • edf
  • frp
  • EDF
  • FRP
  • INHB
Epitope
AA 85-112, N-Term
18
16
12
10
9
5
5
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
68
28
17
9
8
6
5
2
1
Host
Rabbit
99
7
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
14
13
3
2
2
2
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
74
65
39
19
18
15
13
7
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This INHBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-112 AA from the N-terminal region of human INHBA.
Clone RB20703
Isotype Ig
Specificity This INHBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-119 amino acids from the N-terminal region of human INHBA.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name INHBA (INHBA Antibody Abstract)
Background The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Synonyms: Inhibin beta A chain,INHBA,
Molecular Weight 47442 DA
Gene ID 3624
NCBI Accession NP_002183
UniProt P08476
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Inhibin, beta A (INHBA) (AA 85-112), (N-Term) antibody (ABIN655078) INHBA Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).T...
Immunohistochemistry (IHC) image for anti-Inhibin, beta A (INHBA) (AA 85-112), (N-Term) antibody (ABIN655078) INHBA Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin ...
Immunofluorescence (IF) image for anti-Inhibin, beta A (INHBA) (AA 85-112), (N-Term) antibody (ABIN655078) Confocal immunofluorescent analysis of INHBA Antibody (N-term) with HepG2 cell follow...
Flow Cytometry (FACS) image for anti-Inhibin, beta A (INHBA) (AA 85-112), (N-Term) antibody (ABIN655078) INHBA Antibody (N-term) flow cytometric analysis of CEM cells (right histogram) comp...
Background publications Canzian, Cox, Setiawan et al.: "Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium." in: Human molecular genetics, Vol. 19, Issue 19, pp. 3873-84, 2010 (PubMed).