IFT88 antibody (C-Term)

Catalog No. ABIN655090

Product Details anti-IFT88 Antibody

Target: IFT88 (Intraflagellar Transport 88 Homolog (IFT88))

Binding Specificity: AA 791-820, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT88 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IFT88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 791-820 amino acids from the C-terminal region of human IFT88.

Clone: RB24875

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-IFT88 antibody (ABIN655090)

Xiang, Guo, Cheng, Zhang, Huang, Wang, Ma, Xu: "HDAC6 inhibition suppresses chondrosarcoma by restoring the expression of primary cilia." in: Oncology reports, Vol. 38, Issue 1, pp. 229-236, (2018) (PubMed).

Zhan, Xiang, Guo, Ma: "Basic fibroblast growth factor increases IFT88 expression in chondrocytes." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 6590-6599, (2018) (PubMed).

Xiang, Jiang, Guo, Gong, Yang, Wu, Huang, Cheng, Xu: "Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis." in: Oncology reports, Vol. 32, Issue 4, pp. 1622-30, (2014) (PubMed).

Target Details for IFT88

Target: IFT88 (Intraflagellar Transport 88 Homolog (IFT88))

Alternative Name: IFT88 (IFT88 Products)

Synonyms: 146590_s_at antibody, CG12548 antibody, CG14465 antibody, CG15190 antibody, CG4137 antibody, Dmel\\CG12548 antibody, IFT88 antibody, NOMPB antibody, OSM-5 antibody, Tg737 antibody, nomp antibody, osm-5 antibody, AW552028 antibody, Tg737Rpw antibody, TgN737Rpw antibody, Ttc10 antibody, flexo antibody, fxo antibody, orpk antibody, polaris antibody, D13S1056E antibody, DAF19 antibody, TG737 antibody, TTC10 antibody, hTg737 antibody, intraflagellar transport 88 antibody, intraflagellar transport 88 homolog antibody, intraflagellar transport protein 88 homolog antibody, no mechanoreceptor potential B antibody, IFT88 antibody, ift88 antibody, LOC100518926 antibody, LOC100640298 antibody, LOC100646898 antibody, nompB antibody, Ift88 antibody

Background: This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq].

Gene ID: 8100

NCBI Accession: NP_006522, NP_783195

UniProt: Q13099

Pathways: Hedgehog Signaling, Sensory Perception of Sound