Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L) (N-Term), (AA 91-119) antibody

Details for Product No. ABIN655113
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Antigen
Synonyms DDBDRAFT_0204486, DDBDRAFT_0234100, DDB_0204486, DDB_0234100, int11, CPSF73L, INT11, INTS11, RC-68, RC68, 2410006F12Rik, AU044035, RGD1306841, zgc:110671, CPSF3L, DKFZp469C1432
Epitope
N-Term, AA 91-119
(9), (8), (3), (2), (1), (1)
Reactivity
Human
(17)
Host
Rabbit
(16), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(15), (8), (6), (6), (6), (4), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN655113
291.50 $
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Immunogen This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 AA from the N-terminal region of human CPSF3L.
Clone RB28848
Isotype Ig
Specificity This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human CPSF3L.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CPSF3L
Background The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A, MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1, MIM 180680) and U2 (RNU2, MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).
Synonyms: Integrator complex subunit 11,CPSF3L,INTS11, RC68
Molecular Weight 67663 Da
Gene ID 54973
UniProt Q5TA45
Research Area Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L) (N-Term), (AA 91-119) antibody Confocal immunofluorescent analysis of CPSF3L Antibody (N-term) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
anti-Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L) (N-Term), (AA 91-119) antibody (2) CPSF3L Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CPSF3L antibody detected the CPSF3L protein (arrow).
anti-Cleavage and Polyadenylation Specific Factor 3-Like (CPSF3L) (N-Term), (AA 91-119) antibody (3) CPSF3L Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CPSF3L Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Background publications Baillat, Hakimi, Näär et al.: "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II." in: Cell, Vol. 123, Issue 2, pp. 265-76, 2005 (PubMed).

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