You are viewing an incomplete version of our website. Please click to reload the website as full version.

F-Box Protein, Helicase, 18 (FBXO18) (AA 741-769), (C-Term) antibody

Details for Product No. ABIN655165, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms AU015756, Fbh1, Fbx18, FBH1
AA 741-769, C-Term
(17), (16), (1), (1)
Mouse (Murine)
(23), (18), (6)
(28), (6)
Clonality (Clone)
Polyclonal ()
(2), (2), (2), (2), (2), (2), (1)
Western Blotting (WB)
(27), (20), (3), (3), (2), (1), (1), (1), (1)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 741-769 AA from the C-terminal region of human FBXO18.
Clone RB18055
Isotype Ig
Specificity This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 748-777 amino acids from the C-terminal region of human FBXO18.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FBXO18 (FBXO18 Antibody Abstract)
Background This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms: FBXO18,F-box only protein 18,FBH1, FBX18
Molecular Weight 117686 DA
Gene ID 84893
NCBI Accession NP_835363
UniProt Q8NFZ0
Research Area Cell Structure, Signaling, Chromatin, Metabolism, Transcription Factors
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-F-Box Protein, Helicase, 18 (FBXO18) (AA 741-769), (C-Term) antibody (ABIN655165) FBXO18 Antibody (C-term) (ABIN655165) western blot analysis in mouse heart tissue lys...
Background publications Turnbull, Ahmed, Morrison et al.: "Genome-wide association study identifies five new breast cancer susceptibility loci." in: Nature genetics, Vol. 42, Issue 6, pp. 504-7, 2010 (PubMed).

Fugger, Mistrik, Danielsen et al.: "Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities." in: The Journal of cell biology, Vol. 186, Issue 5, pp. 655-63, 2009 (PubMed).

Chiolo, Saponaro, Baryshnikova et al.: "The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles." in: Molecular and cellular biology, Vol. 27, Issue 21, pp. 7439-50, 2007 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ..." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Catalog No. ABIN655165
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)