F-Box Protein, Helicase, 18 (FBXO18) (C-Term), (AA 741-769) antibody

Details for Product No. ABIN655165
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms AU015756, Fbh1, Fbx18, FBH1
Epitope
C-Term, AA 741-769
(8), (8), (1)
Reactivity
Mouse (Murine)
(22), (21), (14), (12)
Host
Rabbit
(24), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(16), (10), (10), (3), (2), (2)
Pubmed 5 references available
Quantity 400 µL
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN655165
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 741-769 AA from the C-terminal region of human FBXO18.
Clone RB18055
Isotype Ig
Specificity This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 748-777 amino acids from the C-terminal region of human FBXO18.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FBXO18
Background This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms: FBXO18,F-box only protein 18,FBH1, FBX18
Molecular Weight 117686 DA
Gene ID 84893
NCBI Accession NP_835363
UniProt Q8NFZ0
Research Area Cell Structure, Signaling, Chromatin, Metabolism, Transcription Factors
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-F-Box Protein, Helicase, 18 (FBXO18) (C-Term), (AA 741-769) antibody FBXO18 Antibody (C-term) (ABIN655165) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the FBXO18 antibody detected the FBXO18 protein (arrow).
Background publications Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Chiolo, Saponaro, Baryshnikova et al.: "The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles." in: Molecular and cellular biology, Vol. 27, Issue 21, pp. 7439-50, 2007 (PubMed).

Fugger, Mistrik, Danielsen et al.: "Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities." in: The Journal of cell biology, Vol. 186, Issue 5, pp. 655-63, 2009 (PubMed).

Turnbull, Ahmed, Morrison et al.: "Genome-wide association study identifies five new breast cancer susceptibility loci." in: Nature genetics, Vol. 42, Issue 6, pp. 504-7, 2010 (PubMed).

Validation Images
Did you look for something else?
back to top