You are viewing an incomplete version of our website. Please click to reload the website as full version.

F-Box Protein, Helicase, 18 (FBXO18) (AA 741-769), (C-Term) antibody

Details for Product No. ABIN655165, Supplier: Log in to see
Antigen
  • AU015756
  • Fbh1
  • Fbx18
  • FBH1
Epitope
AA 741-769, C-Term
17
16
1
1
Reactivity
Mouse (Murine)
23
18
6
Host
Rabbit
28
6
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
1
Application
Western Blotting (WB)
27
20
3
3
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 741-769 AA from the C-terminal region of human FBXO18.
Clone RB18055
Isotype Ig
Specificity This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 748-777 amino acids from the C-terminal region of human FBXO18.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FBXO18 (FBXO18 Antibody Abstract)
Background This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms: FBXO18,F-box only protein 18,FBH1, FBX18
Molecular Weight 117686 DA
Gene ID 84893
NCBI Accession NP_835363
UniProt Q8NFZ0
Research Area Cell Structure, Signaling, Chromatin, Metabolism, Transcription Factors
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-F-Box Protein, Helicase, 18 (FBXO18) (AA 741-769), (C-Term) antibody (ABIN655165) FBXO18 Antibody (C-term) (ABIN655165) western blot analysis in mouse heart tissue lys...
Background publications Turnbull, Ahmed, Morrison et al.: "Genome-wide association study identifies five new breast cancer susceptibility loci." in: Nature genetics, Vol. 42, Issue 6, pp. 504-7, 2010 (PubMed).

Fugger, Mistrik, Danielsen et al.: "Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities." in: The Journal of cell biology, Vol. 186, Issue 5, pp. 655-63, 2009 (PubMed).

Chiolo, Saponaro, Baryshnikova et al.: "The human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles." in: Molecular and cellular biology, Vol. 27, Issue 21, pp. 7439-50, 2007 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. ..." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).