You are viewing an incomplete version of our website. Please click to reload the website as full version.

GAD antibody (Glutamate Decarboxylase 1 (Brain, 67kDa)) (AA 514-543)

Details for Product anti-GAD1 Antibody No. ABIN655175, Supplier: Log in to see
Antigen
  • AO090005000539
  • AO090103000342
  • AW822034
  • C88048
  • cpsq1
  • CPSQ1
  • EP10
  • GAD
  • gad
  • Gad-1
  • GAD-67
  • gad1
  • GAD1
  • gad1-A
  • GAD2
  • GAD25
  • GAD44
  • Gad67
  • GAD67
  • gad67
  • GLUTAMATE DECARBOXYLASE
  • glutamate decarboxylase
  • GLUTAMATE DECARBOXYLASE 1
  • MKP11.30
  • MKP11_30
  • PGP9.5
  • PGP 9.5
  • R75593
  • SCP
  • UCH-L1
  • UCHL-1
Epitope
AA 514-543, C-Term
35
20
16
15
13
8
6
6
6
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
142
68
60
10
7
7
2
1
1
1
1
1
Host
Rabbit
116
29
18
3
Clonality (Clone)
Polyclonal ()
Conjugate
This GAD antibody is un-conjugated
7
7
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
131
66
38
30
11
10
7
7
4
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen This GAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 514-543 AA from the C-terminal region of human GAD1.
Clone RB19329
Isotype Ig
Specificity This GAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-551 amino acids from the C-terminal region of human GAD1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GAD1 (GAD1 Antibody Abstract)
Background This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Synonyms: GAD1,Glutamate decarboxylase 1,GAD, GAD67
Molecular Weight 66897 DA
Gene ID 2571
NCBI Accession NP_000808
UniProt Q99259
Research Area Cell Structure, Metabolism
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.27 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-GAD antibody (Glutamate Decarboxylase 1 (Brain, 67kDa)) (AA 514-543) (ABIN655175) GAD1 Antibody (C-term) (ABIN655175) western blot analysis in HepG2 cell line lysates ...
Background publications Ruaño, Thompson, Kane, Pullinger, Windemuth, Seip, Kocherla, Holford, Wu: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010