DDB1 and CUL4 Associated Factor 16 (DCAF16) (C-Term) antibody

Antigen: DDB1 and CUL4 Associated Factor 16 (DCAF16)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655229

Additional Information

Alternative name: C4orf30

Gene ID: 54876

UniProt: Q9NXF7, NP_060211.3

Immunogen: This C4orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-181 amino acids from the C-terminal region of human C4orf30.

Isotype: Ig

Description: Other names: DCAF16,DDB1- and CUL4-associated factor 16,C4orf30

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This C4orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-181 amino acids from the C-terminal region of human C4orf30.

Molecular Weight: 24193 DA

Comments:

Background: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure, Protein Modifications, Signaling

Restrictions: For Research Use only

Images

C4orf30 Antibody (C-term) (ABIN655229) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Publications

Product: Jin, Arias, Chen et al.: "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1." in: Molecular cell, Vol. 23, Issue 5, pp. 709-21, 2006 (PubMed).

Okada, Kamatani, Takahashi et al.: "A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci." in: Human molecular genetics, Vol. 19, Issue 11, pp. 2303-12, 2010 (PubMed).